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[Music]

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by some sort of serendipity or

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synchronicity what's been on my mind the

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last year or two happens to fit

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perfectly into the theme of this

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conference of challenging mainstream

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paradigms and my challenge is to the

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routine treatment of chronic diseases

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with drugs which focuses on symptoms

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instead of causes and it really reflects

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an unwitting unspoken implicit

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assumption that we can extend lifespan

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indefinitely by administering drugs so

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I've called this seeking immortality

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with a question mark not a cold and as

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in the as in the program and some of the

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statements I make may strike you as

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maybe a bit excessive overblown in fact

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I'll be a bit disappointed if they don't

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but everything I say is based on

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mainstream documentation and on my

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website there's a PDF you can download

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what's wrong with with medicine that has

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dozens of books a number of articles

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some official reports all of which state

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or document what I'm about to tell you

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and in fact I think this is more a

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when when we don't feel well it's for

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broadly one of two reasons either we've

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been attacked from outside in which case

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we talk about an infectious disease or

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there's some sort of malfunction inside

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ourselves there's a chronic disease like

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heart disease or cancer or arthritis

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that sort of thing those are two very

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different ways of getting to feel ill so

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you might think that we ought to treat

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them differently but we don't current

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practice is in both cases to attempt to

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treat them with drugs which are

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supposedly specific and do only what we

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want them to do when it in the case of

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an infectious disease we can identify a

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specific cause of illness not only that

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but bacteria and parasites have

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physiologies that are sufficiently

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different from our physiology that we

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can find we have found substances that

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can kill them differentially kill them

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without killing us at least sufficiently

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differently and what's more to get over

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an infectious disease we usually have to

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take a drug for a limited period of time

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by contrast groups in the case of the

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malfunction inside of chronic disease

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there is no specific identifiable cause

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no single cause it's a

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systemic disturbance and the question is

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if you want to cure that it means

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restoring homeostasis which refers to

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the fact that our bodies manage to

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function in a stable way a reasonably

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stable way even though they're immensely

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complicated systems there are

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innumerable reactions going on all the

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time those reactions are switched on and

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off by signals that go back and forth

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there's feedback all the time and it's

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an intensely complex system where it

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doesn't seem rational to think that when

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you that you can fix something wrong

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with that system just by adding one

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substance what's more if it's a chronic

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disease we are being administered drugs

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for lifelong use and in that case our

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systems are also being affected by the

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cumulative effects of the so called

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side effects now when I say that there's

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no specific identifiable cause of

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illness current theory is that cancer

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for example requires several steps to

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occur and no single one of those is

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decisive not a single one alone will

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cause the cancer as far as heart disease

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cardiovascular disease goes the

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Institute of Medicine mentions that

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there are 243 risk factors for that

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so there's obviously no way in which you

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can treat 243 different risks certainly

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not with drugs

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so having said that there's no single

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identifiable cause of chronic disease

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I'm going to tell you that there is a

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single clear cause of chronic disease

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it's getting older if someone dies from

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heart disease from cancer what does the

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death certificate say what do we say

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about it we say this person died from

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so the thought that we can prevent organ

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failure or cancer amounts to saying that

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we can prevent aging and that's why I

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chose the title seeking immortality

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that's implicitly what we are doing

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without of course admitting it and one

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way of disguising that fact is to

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describe getting older as though it were

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an illness we use semantics normal

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changes with age are described as

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abnormal we don't talk about our hearts

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and arteries getting older we say we've

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got cardiovascular disease as though it

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were the same sort of thing as when we

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get the flu we talk about hypertension

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blood pressure too high pre hypertension

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you're not healed yet but you're going

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to be and I'm gonna say a lot more about

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blood pressure later we talk about

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pre-diabetes talked about high

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cholesterol and bad cholesterol when

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actually cholesterol is one of the

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substances our body makes because it

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needs the cholesterol the cholesterol is

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part of

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all of the cell membranes we talk about

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dysfunctions clearly things all of these

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things happen normally with age but we

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described them as though they were

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abnormalities so what I've said so far

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is is really based on first principles

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on first principles he wouldn't think

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that you could cure chronic diseases

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with drugs but we've been doing it we've

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been trying it for decades so there

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ought to be some evidence as to whether

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it works or not we've been taking blood

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pressure lowering medications and blood

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thinners and statins and the question is

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have they improved the quality of life

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or have they extended useful lifespan

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how would you answer that question

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well you would have to take people pairs

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of people who have exactly the same

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condition and you would have to treat

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one of them and leave the other one

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untreated and they would also have to be

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matched for everything that could

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possibly be important like age sex

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genetic predisposition environment diet

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lifestyle it is impossible to do that

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sort of a clinical trial so what do we

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do we use so called biomarkers or

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surrogate markers we measure blood

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pressure we measure cholesterol level we

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measure blood sugar PSA and so on on the

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presumption that those things that we

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can measure are proper measures of the

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disease that we are trying or the

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condition that we are attempting to to

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follow well are the surrogate markers

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valid

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in order to find out whether any given

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surrogate marker is valid you would have

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to do exactly the sort of impossible

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clinical trial as you would have needed

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to test a drug so these biomarkers blood

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pressure cholesterol level and so on had

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been chosen because they have been found

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to be associated statistically

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correlated statistically with what we've

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called the disease now a statistical

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correlation may not be valid in

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individual cases the overall mortality

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increases as blood pressure increases

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but given individuals may thrive on

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blood pressure levels that are 50

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percent higher than the average the

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statistical correlation does not

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transfer over to any individual case but

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in any case all of these surrogate

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markers are based just on correlations

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and it's a fundamental fact of

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statistics and of common sense that

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correlation doesn't prove causation my

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favorite example of that comes from

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books 60 years ago by Darrell half how

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to lie with statistics and he mentions

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the correlation between the price of

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ramen Cuba and the salaries of

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Protestant ministers in Connecticut the

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question is is it the fact that those

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ministers salaries were going up that

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allowed Cuba to to ask more forum well

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obviously not the fact is that prices

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and salaries both increased with

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inflation and so there was a correlation

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between those two things we tend to

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believe that correlations show causes

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when it seems plausible but the evidence

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just the correlation doesn't prove the

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cause as we get older the incidence of

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cancer increases statistically speaking

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incidence of organ failures increases

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the incidence of heart attacks and

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strokes increases hearing deteriorate

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incidence of dementia increases blood

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pressure increases mortality increases

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all those things correlate with one

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another so does that mean that blood

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pressure causes cancer hearing loss the

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main TIA

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they're just correlations but not

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everybody seems to understand that about

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six months ago there were some news

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items over about a research study which

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had found a correlation between hearing

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loss and de mentir

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and there was even speculation about why

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that might be as as it gets harder and

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harder to hear you stress your brain and

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you drive yourself nuts trying to

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understand what's being said shortly

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after that my local newspaper carried

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this full-page ad saying hearing loss

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and de mentir linked and of course they

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suggested that everyone should get their

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hearing tested and if there was any

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deficiency there they should get a

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hearing aid in order to stave off

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Alzheimer's disease that seems absurd

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but you see the evidence that high blood

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pressure causes cardiovascular disease

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is of exactly the same sort as the

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evidence that hearing loss causes demand

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here or that demand here causes hearing

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loss so the surrogate markers are simply

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not valid and I'm not the person who

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suggests that an Institute of Medicine

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report published in 2010 called the

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evaluation of biomarkers and surrogate

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endpoints in chronic disease actually

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amounts to an attempt to advise how to

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minimize the damage from using surrogate

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markers and they mentioned some

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surrogate markers that are not valid for

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example in the case of cancers it turns

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out that the size of a tumor is not a

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valid measure that tells you about the

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prognosis of what is likely to happen in

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cardiovascular disease believe it or not

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they the Institute of Medicine says

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blood pressure is not a valid marker of

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the progression of cardiovascular

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disease neither is cholesterol whether

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it's total or the so called bad

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cholesterol or the ratio neither is the

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c-reactive protein which has been in

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fashion or another substance troponin

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Javan an EDL in the British Medical

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Journal last year talked about the true

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cost of using drugs to prevent disease

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and they said flatly

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there are no valid data on the

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effectiveness of statins

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antihypertensives

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and bisphosphonates

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be aimed at antihypertensives lower

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blood pressure bisphosphonates are what

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we get in order to stave off supposedly

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osteoporosis so I'm suggesting that the

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drug based treatment of chronic ailments

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is a fundamentally misguided approach it

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treats aging as though it were an

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illness the illness is assessed by

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surrogate markers drugs are approved on

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the basis of how they affect the

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surrogate markers and then we add to

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that the wrong presumption the drugs can

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be specific there are many sins in the

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approval process of drugs one of them is

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that in order to get a drug approved all

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you have to do is to submit to the

282
00:18:53,650 --> 00:18:50,030
Federal Drug Administration the results

283
00:18:57,520 --> 00:18:53,660
of two clinical trials which have lasted

284
00:18:59,860 --> 00:18:57,530
at least six months you don't have to

285
00:19:04,450 --> 00:18:59,870
tell them how many other trials you

286
00:19:08,520 --> 00:19:04,460
carried out that accelerated approval

287
00:19:14,320 --> 00:19:08,530
was brought in as a result of the panic

288
00:19:17,620 --> 00:19:14,330
over the AIDS epidemic when there was

289
00:19:21,460 --> 00:19:17,630
apparently no cure available but it has

290
00:19:24,450 --> 00:19:21,470
become routine one of the things that

291
00:19:27,640 --> 00:19:24,460
was supposed to be part of accelerated

292
00:19:28,420 --> 00:19:27,650
approval was that after a drug had been

293
00:19:30,940 --> 00:19:28,430
approved

294
00:19:34,750 --> 00:19:30,950
there should be continual monitoring of

295
00:19:37,660 --> 00:19:34,760
what it actually did in practice but

296
00:19:41,880 --> 00:19:37,670
there's been a thoroughgoing failure to

297
00:19:45,250 --> 00:19:41,890
do that and it turns out that about

298
00:19:51,280 --> 00:19:45,260
three-quarters of all drugs approved in

299
00:19:54,070 --> 00:19:51,290
this way have no data from follow-up and

300
00:20:03,360 --> 00:19:54,080
in fact there is no system

301
00:20:12,070 --> 00:20:06,220
doctors individual physicians of course

302
00:20:17,520 --> 00:20:12,080
are asked to report when they see that a

303
00:20:20,140 --> 00:20:17,530
particular drug has had a bad effect but

304
00:20:23,610 --> 00:20:20,150
individual doctors are given no

305
00:20:29,350 --> 00:20:23,620
guidelines for the various medications

306
00:20:31,330 --> 00:20:29,360
for what they should look for so you're

307
00:20:33,910 --> 00:20:31,340
a doctor you're treating someone for a

308
00:20:36,310 --> 00:20:33,920
particular condition you're using a drug

309
00:20:39,850 --> 00:20:36,320
that's been approved by the FDA

310
00:20:42,490 --> 00:20:39,860
you presume that it's working you find

311
00:20:44,740 --> 00:20:42,500
you you notice that the patient is not

312
00:20:48,460 --> 00:20:44,750
getting better maybe showing some other

313
00:20:51,340 --> 00:20:48,470
symptoms the most natural thing for you

314
00:20:54,610 --> 00:20:51,350
to conclude is the drug isn't really

315
00:20:58,000 --> 00:20:54,620
helping the illness is getting worse but

316
00:21:01,090 --> 00:20:58,010
you don't immediately believe that maybe

317
00:21:05,320 --> 00:21:01,100
the drug is causing an additional

318
00:21:08,740 --> 00:21:05,330
problem so even if there were some sort

319
00:21:11,680 --> 00:21:08,750
of a system of reporting adverse events

320
00:21:14,860 --> 00:21:11,690
there is no guarantee that it would be

321
00:21:19,510 --> 00:21:14,870
could be efficient and in fact some

322
00:21:22,960 --> 00:21:19,520
observers have suggested that maybe 90%

323
00:21:26,830 --> 00:21:22,970
of the adverse effects of drugs are

324
00:21:29,290 --> 00:21:26,840
never reported to the authorities now

325
00:21:35,640 --> 00:21:29,300
those were sins of omission

326
00:21:42,540 --> 00:21:39,460
those two clinical trials on the basis

327
00:21:46,090 --> 00:21:42,550
of which the FDA may approve a drug and

328
00:21:49,440 --> 00:21:46,100
not of course the last data that we get

329
00:21:53,230 --> 00:21:49,450
about the effects of those drugs and

330
00:21:57,910 --> 00:21:53,240
John yo-yo our need is who has done a

331
00:22:04,650 --> 00:21:57,920
lot of statistical assessment of medical

332
00:22:06,159 --> 00:22:04,660
matters looked at the 35 most cited

333
00:22:10,989 --> 00:22:06,169
biomarker

334
00:22:16,959 --> 00:22:10,999
and he found that in only seven of those

335
00:22:20,409 --> 00:22:16,969
35 cases did later data confirmed what

336
00:22:25,349 --> 00:22:20,419
those in to initial clinical trials had

337
00:22:29,979 --> 00:22:25,359
claimed even if the clinical trials were

338
00:22:34,779 --> 00:22:29,989
valid there's always a problem because

339
00:22:38,139 --> 00:22:34,789
the clinical trials do not look at the

340
00:22:41,769 --> 00:22:38,149
people who will be treated with the drug

341
00:22:43,810 --> 00:22:41,779
after it has been approved they are part

342
00:22:46,930 --> 00:22:43,820
of that's inevitable and makes a lot of

343
00:22:49,810 --> 00:22:46,940
sense if you want to consider whether

344
00:22:52,209 --> 00:22:49,820
something lowers blood pressure you're

345
00:22:55,089 --> 00:22:52,219
going to do a clinical trial with people

346
00:22:57,219 --> 00:22:55,099
who have very high blood pressure it

347
00:23:00,070 --> 00:22:57,229
gives you the best chance of seeing

348
00:23:03,039 --> 00:23:00,080
whether the drug works so you try it out

349
00:23:05,619 --> 00:23:03,049
on people who's whose systolic is a

350
00:23:08,619 --> 00:23:05,629
hundred and eighty or 200 something like

351
00:23:12,119 --> 00:23:08,629
that you find it works the drug is

352
00:23:16,060 --> 00:23:12,129
approved and then doctors prescribe it

353
00:23:18,909 --> 00:23:16,070
to people whose blood pressure may be a

354
00:23:22,299 --> 00:23:18,919
hundred and forty and not a hundred and

355
00:23:26,320 --> 00:23:22,309
eighty or 200 so there's no guarantee

356
00:23:29,639 --> 00:23:26,330
from the clinical trial that those

357
00:23:33,269 --> 00:23:29,649
results can be transferred to the

358
00:23:37,029 --> 00:23:33,279
population that will actually be treated

359
00:23:42,039 --> 00:23:37,039
it's also the case that individual

360
00:23:46,209 --> 00:23:42,049
doctors can prescribe any approved drug

361
00:23:50,820 --> 00:23:46,219
for any condition not necessarily those

362
00:23:57,629 --> 00:23:50,830
that it's been approved for and a recent

363
00:24:01,989 --> 00:23:57,639
survey indicated that three-quarters of

364
00:24:06,159 --> 00:24:01,999
the off lay these off-label uses of

365
00:24:10,709 --> 00:24:06,169
drugs have no scientific evidence to

366
00:24:15,249 --> 00:24:10,719
back them up 20% of all prescriptions

367
00:24:18,729 --> 00:24:15,259
are written for conditions for which the

368
00:24:19,720 --> 00:24:18,739
drug was not actually approved in the

369
00:24:22,490 --> 00:24:19,730
case of the

370
00:24:27,100 --> 00:24:22,500
psychotropic drugs for mental illnesses

371
00:24:31,120 --> 00:24:27,110
it's actually 30% one-third of the drugs

372
00:24:33,620 --> 00:24:31,130
antidepressants antipsychotics and so on

373
00:24:37,880 --> 00:24:33,630
prescriptions are written by doctors

374
00:24:41,000 --> 00:24:37,890
presumably up usually psychiatrists when

375
00:24:44,900 --> 00:24:41,010
that particular application of that drug

376
00:24:48,410 --> 00:24:44,910
was never approved and I've already

377
00:24:51,020 --> 00:24:48,420
mentioned that correlations a mistake

378
00:24:56,650 --> 00:24:51,030
and should not be mistaken for causes

379
00:25:02,180 --> 00:24:56,660
but the the terminology risk factor is

380
00:25:05,930 --> 00:25:02,190
very sneaky it makes you think that a

381
00:25:08,410 --> 00:25:05,940
risk factor actually is a risk but it

382
00:25:14,060 --> 00:25:08,420
isn't the risk factor is purely a

383
00:25:16,850 --> 00:25:14,070
statistical Association another sin of

384
00:25:20,720 --> 00:25:16,860
common sin of comission is that when the

385
00:25:23,300 --> 00:25:20,730
results of clinical trials are reported

386
00:25:26,720 --> 00:25:23,310
and remember that the people who do the

387
00:25:30,520 --> 00:25:26,730
clinical trials are the drug companies

388
00:25:33,080 --> 00:25:30,530
or organizations contract research

389
00:25:36,110 --> 00:25:33,090
organizations hired by the drug

390
00:25:38,810 --> 00:25:36,120
companies to do the trials so they'll

391
00:25:42,410 --> 00:25:38,820
present the data in in what looks like

392
00:25:45,320 --> 00:25:42,420
the most impressive way so you found

393
00:25:47,870 --> 00:25:45,330
something that lowers the mortality from

394
00:25:50,690 --> 00:25:47,880
a particular condition from four per

395
00:25:54,200 --> 00:25:50,700
hundred to two per hundred and you

396
00:25:57,560 --> 00:25:54,210
report this as a 50% reduction in

397
00:26:01,190 --> 00:25:57,570
mortality well I mean who is not going

398
00:26:06,770 --> 00:26:01,200
to buy a drug that reduces your risk of

399
00:26:10,100 --> 00:26:06,780
dying by 50% but it doesn't it reduces

400
00:26:14,570 --> 00:26:10,110
it by two percent in this case and in

401
00:26:18,170 --> 00:26:14,580
that case the possible side effects may

402
00:26:21,830 --> 00:26:18,180
be worse than the potential reduction of

403
00:26:24,650 --> 00:26:21,840
risk so we have sins of omission and

404
00:26:29,810 --> 00:26:24,660
Commission in the approval of drugs and

405
00:26:33,080 --> 00:26:29,820
there are wages of sin in the 1950s to

406
00:26:36,830 --> 00:26:33,090
nineteen sixties to prescription drug

407
00:26:41,290 --> 00:26:36,840
were withdrawn from use in the 1970s

408
00:26:44,390 --> 00:26:41,300
another - in the 1980s five after

409
00:26:50,030 --> 00:26:44,400
accelerated approval was introduced in

410
00:26:53,230 --> 00:26:50,040
the 1990s 15 drugs were were withdrawn

411
00:26:56,900 --> 00:26:53,240
had to be withdrawn and in the 2000s

412
00:27:00,530 --> 00:26:56,910
twenty six drugs had to be withdrawn and

413
00:27:03,650 --> 00:27:00,540
what's more the time between approval

414
00:27:05,090 --> 00:27:03,660
and withdrawal has been getting shorter

415
00:27:08,540 --> 00:27:05,100
and shorter

416
00:27:11,360 --> 00:27:08,550
the anti-diabetic rezulin was on the

417
00:27:14,840 --> 00:27:11,370
market for only three years before it

418
00:27:18,650 --> 00:27:14,850
was withdrawn the antibiotic racks are

419
00:27:22,820 --> 00:27:18,660
for two years redux to suppress your

420
00:27:26,300 --> 00:27:22,830
appetite was available for only 21

421
00:27:30,670 --> 00:27:26,310
months a calcium channel blocker lasted

422
00:27:33,680 --> 00:27:30,680
a year and analgesic eleven months a

423
00:27:38,060 --> 00:27:33,690
gastrointestinal drug only ten months

424
00:27:41,990 --> 00:27:38,070
now remember there is no systematic way

425
00:27:44,510 --> 00:27:42,000
of gathering information about what a

426
00:27:48,010 --> 00:27:44,520
drug actually does after it's been

427
00:27:53,180 --> 00:27:48,020
approved for so for something to be

428
00:27:55,750 --> 00:27:53,190
withdrawn so soon after approval there

429
00:27:59,960 --> 00:27:55,760
must have been truly horrendous

430
00:28:04,760 --> 00:27:59,970
incidence of side effects and fatalities

431
00:28:08,350 --> 00:28:04,770
in order to produce the evidence for the

432
00:28:16,850 --> 00:28:13,340
one of the other thins that's connected

433
00:28:21,270 --> 00:28:16,860
with drugs is the terminology of side

434
00:28:26,600 --> 00:28:23,200
[Music]

435
00:28:28,910 --> 00:28:26,610
side effect sounds as though it is

436
00:28:34,160 --> 00:28:28,920
something doesn't always occur is

437
00:28:38,870 --> 00:28:34,170
typically negligible and so on but any

438
00:28:42,470 --> 00:28:38,880
given drug has many effects and one of

439
00:28:46,100 --> 00:28:42,480
the indications of that is the penchant

440
00:28:49,870 --> 00:28:46,110
the drug companies have increasingly to

441
00:28:52,490 --> 00:28:49,880
reposition drugs what does that mean

442
00:28:57,140 --> 00:28:52,500
once the drug has been approved its

443
00:29:00,050 --> 00:28:57,150
approved for a particular condition drug

444
00:29:03,350 --> 00:29:00,060
companies are keen to get it approved to

445
00:29:05,470 --> 00:29:03,360
treat other things also because getting

446
00:29:08,420 --> 00:29:05,480
that approval is quicker and cheaper

447
00:29:13,760 --> 00:29:08,430
because after a drug has been once

448
00:29:15,800 --> 00:29:13,770
approved its regarded as safe and so you

449
00:29:18,590 --> 00:29:15,810
don't have to prove that again if it's

450
00:29:22,360 --> 00:29:18,600
going to be repositioned for something

451
00:29:27,710 --> 00:29:22,370
else you've probably all seen ads for

452
00:29:31,400 --> 00:29:27,720
cymbalta on television it was originally

453
00:29:35,240 --> 00:29:31,410
approved to treat anxiety and depression

454
00:29:38,020 --> 00:29:35,250
and peripheral neuropathy loss of

455
00:29:42,110 --> 00:29:38,030
feeling in the extremities and

456
00:29:44,690 --> 00:29:42,120
fibromyalgia peculiarly enough all at

457
00:29:49,070 --> 00:29:44,700
the same dosage even though those are

458
00:29:52,220 --> 00:29:49,080
very different conditions still the

459
00:29:55,130 --> 00:29:52,230
company was looking for better sales and

460
00:29:58,940 --> 00:29:55,140
so they successfully repositioned it

461
00:30:03,710 --> 00:29:58,950
under a different name to treat stress

462
00:30:08,050 --> 00:30:03,720
urinary incontinence now it's not only

463
00:30:11,890 --> 00:30:08,060
the drugs have many different effects

464
00:30:15,400 --> 00:30:11,900
they can have mutually contradictory

465
00:30:20,570 --> 00:30:15,410
effects for instance for this cymbalta

466
00:30:23,890 --> 00:30:20,580
duloxetine the company lists as possible

467
00:30:28,430 --> 00:30:23,900
side effects increased urination and

468
00:30:31,370 --> 00:30:28,440
also difficulty urinating it may cause

469
00:30:34,750 --> 00:30:31,380
constipation or it may cause diarrhea

470
00:30:38,370 --> 00:30:34,760
and it may cause agitation

471
00:30:43,870 --> 00:30:38,380
or it may cause drowsiness and

472
00:30:47,549 --> 00:30:43,880
unresponsiveness so side-effects is a

473
00:30:51,070 --> 00:30:47,559
thoroughly misleading term side

474
00:30:53,409 --> 00:30:51,080
indicates implies that it's unintended

475
00:30:54,730 --> 00:30:53,419
that it's atypical that it's not

476
00:30:57,640 --> 00:30:54,740
important

477
00:31:00,960 --> 00:30:57,650
but the drug doesn't know what it's

478
00:31:05,530 --> 00:31:00,970
intended to do it just carries out its

479
00:31:09,730 --> 00:31:05,540
chemical action a side effect sounds as

480
00:31:13,210 --> 00:31:09,740
though it showed up only infrequently in

481
00:31:16,990 --> 00:31:13,220
only a few people but that's in the

482
00:31:19,780 --> 00:31:17,000
typically short clinical trials if

483
00:31:23,169 --> 00:31:19,790
something shows up as a side effect in

484
00:31:26,110 --> 00:31:23,179
six months then you may be pretty sure

485
00:31:30,130 --> 00:31:26,120
that when people start taking this for

486
00:31:35,100 --> 00:31:30,140
years that those side effects and others

487
00:31:42,659 --> 00:31:38,650
what we are doing nowadays with chronic

488
00:31:48,580 --> 00:31:42,669
diseases is we're actually treating

489
00:31:52,210 --> 00:31:48,590
symptom free illness a very informative

490
00:31:55,960 --> 00:31:52,220
book by jerry jeremy green who is an MD

491
00:32:00,490 --> 00:31:55,970
and a medical historian book is called

492
00:32:02,400 --> 00:32:00,500
prescribing by numbers relates how over

493
00:32:06,720 --> 00:32:02,410
the course of the last half century

494
00:32:12,340 --> 00:32:06,730
approximately lab tests have come to

495
00:32:15,210 --> 00:32:12,350
supersede clinical examination and I'm

496
00:32:19,030 --> 00:32:15,220
sure that you're all familiar with the

497
00:32:21,370 --> 00:32:19,040
mantra know your numbers know what your

498
00:32:26,409 --> 00:32:21,380
cholesterol level is your blood sugar

499
00:32:31,000 --> 00:32:26,419
your blood pressure and so on now it

500
00:32:34,770 --> 00:32:31,010
used to be that blood pressure that was

501
00:32:39,270 --> 00:32:34,780
too high hypertension would be diagnosed

502
00:32:42,580 --> 00:32:39,280
because people felt ill in some way

503
00:32:46,710 --> 00:32:42,590
severe headache dizziness blurred vision

504
00:32:47,800 --> 00:32:46,720
chest pain that's not the modern

505
00:32:51,340 --> 00:32:47,810
diagnosis

506
00:32:54,370 --> 00:32:51,350
of hypertension you may have none of

507
00:32:57,460 --> 00:32:54,380
those symptoms you can feel perfectly

508
00:33:01,060 --> 00:32:57,470
well you can climb stairs without

509
00:33:04,410 --> 00:33:01,070
getting out of breath but if your blood

510
00:33:08,350 --> 00:33:04,420
pressure is greater than 140 over 90

511
00:33:15,300 --> 00:33:08,360
you're told you have hypertension and

512
00:33:21,730 --> 00:33:18,810
not long after measuring blood pressure

513
00:33:25,540 --> 00:33:21,740
became routine because the technique

514
00:33:28,690 --> 00:33:25,550
became easy there was a rule of thumb in

515
00:33:31,300 --> 00:33:28,700
the medical profession that the normal

516
00:33:37,030 --> 00:33:31,310
blood pressure is your age plus a

517
00:33:40,120 --> 00:33:37,040
hundred I looked at a bunch of datasets

518
00:33:43,320 --> 00:33:40,130
from different sources and I think that

519
00:33:46,330 --> 00:33:43,330
those actually show it's more like

520
00:33:53,800 --> 00:33:46,340
two-thirds or three-quarters of your age

521
00:33:57,570 --> 00:33:53,810
plus a hundred is normal with healthy

522
00:34:00,370 --> 00:33:57,580
individuals who don't feel any illness

523
00:34:04,180 --> 00:34:00,380
but here's what the National Institutes

524
00:34:06,190 --> 00:34:04,190
of Health says normal blood pressure is

525
00:34:11,100 --> 00:34:06,200
lower than a hundred and twenty over

526
00:34:14,260 --> 00:34:11,110
eighty most of the time in other words

527
00:34:17,500 --> 00:34:14,270
approximately twenty to thirty year old

528
00:34:21,580 --> 00:34:17,510
a person normally has in blood pressure

529
00:34:24,400 --> 00:34:21,590
high blood pressure hypertension is a

530
00:34:27,070 --> 00:34:24,410
hundred and forty over ninety most or

531
00:34:30,160 --> 00:34:27,080
above most of the time and if you're

532
00:34:36,400 --> 00:34:30,170
between those two you have pre

533
00:34:39,000 --> 00:34:36,410
hypertension and very helpfully the NIH

534
00:34:43,120 --> 00:34:39,010
tells you if you have pre hypertension

535
00:34:44,490 --> 00:34:43,130
you are more likely to develop high

536
00:34:51,460 --> 00:34:44,500
blood pressure

537
00:34:55,060 --> 00:34:51,470
normally with age that's absolutely true

538
00:34:58,090 --> 00:34:55,070
if you have pre hypertension all you've

539
00:35:00,070 --> 00:34:58,100
got to do is live a bit longer and

540
00:35:03,340 --> 00:35:00,080
you'll have

541
00:35:06,370 --> 00:35:03,350
full-blown hypertension the result of

542
00:35:09,910 --> 00:35:06,380
this definition is that about one in

543
00:35:14,620 --> 00:35:09,920
three adults in the United States is

544
00:35:18,670 --> 00:35:14,630
said to have hypertension here's a graph

545
00:35:23,670 --> 00:35:18,680
that that shows that situation blood

546
00:35:30,040 --> 00:35:26,950
120 or below is said to be normal and

547
00:35:34,930 --> 00:35:30,050
that is the blood pressure that on

548
00:35:38,590 --> 00:35:34,940
average 20 to 30 year olds have by the

549
00:35:42,220 --> 00:35:38,600
time most people are around 60 years of

550
00:35:47,820 --> 00:35:42,230
age they're at a hundred and forty and

551
00:35:51,040 --> 00:35:47,830
they're about to get hypertension

552
00:35:53,970 --> 00:35:51,050
seventy five to eighty percent of

553
00:35:58,780 --> 00:35:53,980
American seniors under this definition

554
00:36:02,910 --> 00:35:58,790
have hypertension they are sick in the

555
00:36:06,550 --> 00:36:02,920
absence of any symptoms at all and

556
00:36:15,400 --> 00:36:06,560
present practice is to prescribe drugs

557
00:36:20,080 --> 00:36:15,410
for them for lifelong use half a century

558
00:36:23,230 --> 00:36:20,090
ago diuretics were first introduced to

559
00:36:26,650 --> 00:36:23,240
treat high blood pressure which at that

560
00:36:30,130 --> 00:36:26,660
time was if people had severe headaches

561
00:36:36,160 --> 00:36:30,140
dizziness that sort of thing at that

562
00:36:39,760 --> 00:36:36,170
time cardiologists wondered whether that

563
00:36:42,330 --> 00:36:39,770
was a good idea pointing out that the

564
00:36:46,810 --> 00:36:42,340
increase of blood pressure with age

565
00:36:50,110 --> 00:36:46,820
could be an attempt to compensate for

566
00:36:54,190 --> 00:36:50,120
other effects of aging arteries and

567
00:36:57,910 --> 00:36:54,200
veins become less flexible arteries tend

568
00:37:01,990 --> 00:36:57,920
to narrow a little bit but we want blood

569
00:37:06,190 --> 00:37:02,000
to get to the extremities so it may take

570
00:37:08,710 --> 00:37:06,200
more pressure to send it there and the

571
00:37:12,510 --> 00:37:08,720
some of the cardiologists at that time

572
00:37:16,920 --> 00:37:12,520
suggested that the general administer

573
00:37:19,980 --> 00:37:16,930
of drugs to reduce blood pressure was a

574
00:37:28,500 --> 00:37:19,990
very dangerous experiment being carried

575
00:37:32,190 --> 00:37:28,510
out on the population so I'm suggesting

576
00:37:36,900 --> 00:37:32,200
that the drug center treatment of

577
00:37:43,890 --> 00:37:36,910
chronic ailments treats normal aging as

578
00:37:46,980 --> 00:37:43,900
a disease and it prescribes lifelong

579
00:37:51,780 --> 00:37:46,990
drug use irrespective of what the side

580
00:37:55,920 --> 00:37:51,790
effects are and in absence of any valid

581
00:38:01,200 --> 00:37:55,930
evidence of benefit in terms of quality

582
00:38:05,370 --> 00:38:01,210
of life or extension of lifespan which

583
00:38:08,820 --> 00:38:05,380
reminds you of the statement the

584
00:38:14,099 --> 00:38:08,830
operation was successful but patients

585
00:38:16,680 --> 00:38:14,109
died now about a hundred years ago more

586
00:38:22,609 --> 00:38:16,690
than a hundred years ago the Food and

587
00:38:26,070 --> 00:38:22,619
Drug Administration was founded because

588
00:38:29,880 --> 00:38:26,080
in the nineteenth century and by the end

589
00:38:35,780 --> 00:38:29,890
of the 19th century there were quite a

590
00:38:39,450 --> 00:38:35,790
lot of people selling quack remedies and

591
00:38:43,560 --> 00:38:39,460
at that time people talked about the

592
00:38:48,270 --> 00:38:43,570
snake oil salesman peddling panaceas and

593
00:38:50,660 --> 00:38:48,280
Alex's of life I'm suggesting that in

594
00:38:54,530 --> 00:38:50,670
terms of the treatment of chronic

595
00:38:58,560 --> 00:38:54,540
ailments medicine has regressed a

596
00:39:02,510 --> 00:38:58,570
century or more and we now again have

597
00:39:07,050 --> 00:39:02,520
snake oil salesman peddling panaceas and

598
00:39:09,660 --> 00:39:07,060
Alexia's of life except in those days it

599
00:39:13,710 --> 00:39:09,670
was individuals doing the peddling and

600
00:39:18,120 --> 00:39:13,720
now it's corporations pharmaceutical

601
00:39:21,150 --> 00:39:18,130
companies but then again that may not be

602
00:39:23,579 --> 00:39:21,160
so different because nowadays we've

603
00:39:26,280 --> 00:39:23,589
learned also that corporations are

604
00:39:39,790 --> 00:39:38,170
thank you for listening so politely we

605
00:39:42,190 --> 00:39:39,800
do have time for questions are there any

606
00:39:43,359 --> 00:39:42,200
questions for Henry if you if there are

607
00:39:45,339 --> 00:39:43,369
a number of questions could you please

608
00:39:46,300 --> 00:39:45,349
come up if not I'll do my best to kind

609
00:39:48,990 --> 00:39:46,310
of run around and give you the

610
00:39:56,650 --> 00:39:49,000
microphone that I'm holding in my hand

611
00:39:58,180 --> 00:39:56,660
whoops thank you good morning Henry do

612
00:40:02,319 --> 00:39:58,190
you know anything about the difference

613
00:40:03,760 --> 00:40:02,329
between drugs that are what do they call

614
00:40:05,740 --> 00:40:03,770
them you know there's the regular drug

615
00:40:08,650 --> 00:40:05,750
and then there's the prescription

616
00:40:10,089 --> 00:40:08,660
they're generic because some of them I

617
00:40:13,390 --> 00:40:10,099
understand I don't know if that's true

618
00:40:19,750 --> 00:40:13,400
are made in China and do we know what's

619
00:40:22,690 --> 00:40:19,760
even in them if it is only the active

620
00:40:25,690 --> 00:40:22,700
ingredient then there's absolutely no

621
00:40:28,059 --> 00:40:25,700
difference but the thing that people

622
00:40:31,329 --> 00:40:28,069
worry about is that with drugs

623
00:40:35,290 --> 00:40:31,339
manufactured overseas there isn't the

624
00:40:38,920 --> 00:40:35,300
same sort of care taken about what goes

625
00:40:45,260 --> 00:40:38,930
in there in the same way of monitoring

626
00:40:52,550 --> 00:40:49,310
there shouldn't be any difference and in

627
00:40:55,040 --> 00:40:52,560
many cases now generics are actually

628
00:41:01,700 --> 00:40:55,050
made by the same people who made the

629
00:41:05,810 --> 00:41:01,710
prescription drug thank you for a very

630
00:41:09,380 --> 00:41:05,820
exciting talk I want to know the issue

631
00:41:12,200 --> 00:41:09,390
of corporations peddling snake oil in

632
00:41:15,050 --> 00:41:12,210
the name of drugs how do we say

633
00:41:18,020 --> 00:41:15,060
political issue and a social issue of

634
00:41:22,280 --> 00:41:18,030
people are suffering what can an

635
00:41:25,310 --> 00:41:22,290
organization like sse do in terms of

636
00:41:27,320 --> 00:41:25,320
public education to deal with this kind

637
00:41:30,350 --> 00:41:27,330
of a problem it's a worldwide problem

638
00:41:34,160 --> 00:41:30,360
not just in the US your thoughts will be

639
00:41:37,640 --> 00:41:34,170
appreciated thank you very much I mean

640
00:41:40,670 --> 00:41:37,650
this is a problem that is general for

641
00:41:44,030 --> 00:41:40,680
people in academia as well as in in this

642
00:41:51,140 --> 00:41:44,040
society how do you get people to notice

643
00:41:53,630 --> 00:41:51,150
what the evidence is and you know these

644
00:41:56,210 --> 00:41:53,640
things have developed very slowly one of

645
00:42:02,590 --> 00:41:56,220
the things that I found very interesting

646
00:42:05,360 --> 00:42:02,600
was that some decades ago the CEOs of

647
00:42:09,310 --> 00:42:05,370
pharmaceutical companies were people who

648
00:42:15,740 --> 00:42:09,320
had come up through the technical side

649
00:42:18,040 --> 00:42:15,750
when it was first suggested that drug

650
00:42:21,850 --> 00:42:18,050
companies should be allowed to advertise

651
00:42:27,140 --> 00:42:21,860
direct to consumers as we see nowadays

652
00:42:30,700 --> 00:42:27,150
the CEOs of the drug companies said that

653
00:42:36,410 --> 00:42:34,400
nowadays the CEOs of drug companies are

654
00:42:40,250 --> 00:42:36,420
typically people who have come up

655
00:42:43,430 --> 00:42:40,260
through the marketing and sales side so

656
00:42:47,930 --> 00:42:43,440
the whole culture of drug companies has

657
00:42:54,410 --> 00:42:47,940
changed and again this is something that

658
00:42:57,410 --> 00:42:54,420
has been documented but ignored Marcia

659
00:42:58,340 --> 00:42:57,420
Angell who was an editor of the New

660
00:43:02,930 --> 00:42:58,350
England Journal

661
00:43:06,500 --> 00:43:02,940
of Medicine about eight or ten years ago

662
00:43:10,280 --> 00:43:06,510
published a book called how the drug

663
00:43:13,660 --> 00:43:10,290
companies deceive us and what to do

664
00:43:17,270 --> 00:43:13,670
about it now there was a you know a

665
00:43:20,900 --> 00:43:17,280
knowledgeable prominent voice that has

666
00:43:24,590 --> 00:43:20,910
had no effect and part of the reason of

667
00:43:27,680 --> 00:43:24,600
course is that the drug companies make

668
00:43:33,170 --> 00:43:27,690
such big profits that they can support

669
00:43:37,330 --> 00:43:33,180
many congressional campaigns I wish I

670
00:43:42,680 --> 00:43:39,680
well thank you very much for a very

671
00:43:45,200 --> 00:43:42,690
interesting talk you carefully steered

672
00:43:47,780 --> 00:43:45,210
clear of the whole system-wide health

673
00:43:50,290 --> 00:43:47,790
care debate which is going on right now

674
00:43:54,200 --> 00:43:50,300
costing us a bloody fortune but

675
00:43:57,050 --> 00:43:54,210
lifestyle issues seem to be something

676
00:43:58,730 --> 00:43:57,060
that doctors are either ignorant of or

677
00:44:01,460 --> 00:43:58,740
they don't get any kickbacks from that

678
00:44:03,560 --> 00:44:01,470
so they simply don't often suggest them

679
00:44:05,330 --> 00:44:03,570
and they seem to be probably the most

680
00:44:08,350 --> 00:44:05,340
beneficial when it when it come you know

681
00:44:11,690 --> 00:44:08,360
diet and exercise fresh air and so on

682
00:44:13,820 --> 00:44:11,700
but there also are some legitimate basic

683
00:44:16,370 --> 00:44:13,830
research being done like genetic

684
00:44:17,210 --> 00:44:16,380
engineering Cindy Kenyon at University

685
00:44:20,270 --> 00:44:17,220
of California

686
00:44:22,940 --> 00:44:20,280
Aubrey gray speaking of immortality that

687
00:44:28,220 --> 00:44:22,950
type of thing any comments about about

688
00:44:30,920 --> 00:44:28,230
those well it's true that research money

689
00:44:33,650 --> 00:44:30,930
is not available for those things

690
00:44:37,580 --> 00:44:33,660
because other things are more flashy and

691
00:44:42,140 --> 00:44:37,590
and attracted Colin Campbell wrote a

692
00:44:45,620 --> 00:44:42,150
book the China Study in which he talked

693
00:44:48,710 --> 00:44:45,630
about the relationship of diet to cancer

694
00:44:52,850 --> 00:44:48,720
on the basis of work that he himself had

695
00:44:56,090 --> 00:44:52,860
done and he mentions that the only way

696
00:45:00,410 --> 00:44:56,100
he was able to get this work funded was

697
00:45:05,990 --> 00:45:00,420
by calling it studies of cancer and not

698
00:45:09,170 --> 00:45:06,000
studies of nutrition or diet so it's

699
00:45:12,110 --> 00:45:09,180
also the case I think that it's very

700
00:45:17,090 --> 00:45:12,120
difficult to get good data

701
00:45:20,030 --> 00:45:17,100
about lifestyle issues because you have

702
00:45:23,180 --> 00:45:20,040
to depend very much on self-reporting by

703
00:45:24,950 --> 00:45:23,190
people of how they feel and even if

704
00:45:31,850 --> 00:45:24,960
you're honest about it you're not always

705
00:45:33,770 --> 00:45:31,860
right about about what's going on well

706
00:45:36,260 --> 00:45:33,780
as a physician who worked at a heart

707
00:45:39,020 --> 00:45:36,270
hospital with nutrition exercise and

708
00:45:41,770 --> 00:45:39,030
stress reduction and did not believe

709
00:45:46,430 --> 00:45:41,780
that adult onset diabetes is a disease

710
00:45:48,890 --> 00:45:46,440
but rather is a symptom of our society I

711
00:45:51,970 --> 00:45:48,900
found that the medical my medical peers

712
00:45:54,740 --> 00:45:51,980
did not believe what was happening that

713
00:45:58,370 --> 00:45:54,750
that non drug treatment would be so

714
00:46:01,400 --> 00:45:58,380
effective and it actually is a solution

715
00:46:05,390 --> 00:46:01,410
to the multibillion-dollar healthcare

716
00:46:07,280 --> 00:46:05,400
crisis ran in that mid-90s the only

717
00:46:09,260 --> 00:46:07,290
education I could receive was through

718
00:46:11,180 --> 00:46:09,270
pharmaceutical companies so I dropped

719
00:46:16,900 --> 00:46:11,190
out of CME or continuing medical

720
00:46:20,000 --> 00:46:16,910
education the pharmaceutical companies

721
00:46:21,800 --> 00:46:20,010
brainwash physicians and most of them

722
00:46:23,960 --> 00:46:21,810
really just don't believe it or don't

723
00:46:28,790 --> 00:46:23,970
know what's going on so it is a

724
00:46:32,450 --> 00:46:28,800
grassroots issue yeah and you know we

725
00:46:35,300 --> 00:46:32,460
hear the statistics that so much of

726
00:46:38,300 --> 00:46:35,310
health care costs are spent in the last

727
00:46:40,160 --> 00:46:38,310
year or two of life and that older

728
00:46:43,940 --> 00:46:40,170
people are being given so many

729
00:46:47,750 --> 00:46:43,950
medications we could cut the overall

730
00:46:50,660 --> 00:46:47,760
cost of health care dramatically by

731
00:46:56,810 --> 00:46:50,670
stopping doing things that don't do us

732
00:46:59,750 --> 00:46:56,820
any good Henry that was a splendid talk

733
00:47:03,940 --> 00:46:59,760
thank you very much I just want to say

734
00:47:07,370 --> 00:47:03,950
that we are not helpless in the face of

735
00:47:10,580 --> 00:47:07,380
the corporation's the pharmaceutical

736
00:47:13,400 --> 00:47:10,590
companies a couple of years ago there

737
00:47:15,770 --> 00:47:13,410
were two international studies which

738
00:47:19,070 --> 00:47:15,780
really flew under the radar screen

739
00:47:23,180 --> 00:47:19,080
pretty much of the profession showing

740
00:47:23,750 --> 00:47:23,190
that with attention to diet exercise and

741
00:47:28,340 --> 00:47:23,760
stress man

742
00:47:30,830 --> 00:47:28,350
and stopping smoking three force all

743
00:47:34,400 --> 00:47:30,840
heart disease could be eliminated from

744
00:47:38,210 --> 00:47:34,410
this culture and also two-thirds of all

745
00:47:43,010 --> 00:47:38,220
cancers eliminated prevented this is

746
00:47:46,730 --> 00:47:43,020
astonishing stop and when we grope for

747
00:47:49,640 --> 00:47:46,740
what we can do it's already clear you

748
00:47:51,110 --> 00:47:49,650
know that we have potent options and

749
00:47:55,460 --> 00:47:51,120
they're so potent as a matter of fact

750
00:47:57,710 --> 00:47:55,470
that they simply aren't noticed and but

751
00:47:59,990 --> 00:47:57,720
my point is that you know we we are not

752
00:48:04,790 --> 00:48:00,000
helpless I mean we really do have some

753
00:48:08,810 --> 00:48:04,800
big guns to play and the the problem is

754
00:48:11,240 --> 00:48:08,820
to spread that message to everyone who

755
00:48:15,410 --> 00:48:11,250
can benefit from it and there are

756
00:48:20,570 --> 00:48:15,420
powerful forces that oppose it you know

757
00:48:24,130 --> 00:48:20,580
a known side effect of statins is muscle

758
00:48:28,550 --> 00:48:24,140
weakness and it's known also that

759
00:48:32,000 --> 00:48:28,560
statins not only affect the making of

760
00:48:35,540 --> 00:48:32,010
cholesterol but they also affect the

761
00:48:40,820 --> 00:48:35,550
generation of Rubik we known known also

762
00:48:44,920 --> 00:48:40,830
as coenzyme q10 and coenzyme q10 is an

763
00:48:47,900 --> 00:48:44,930
essential ingredient in every energy

764
00:48:53,170 --> 00:48:47,910
producing reaction in every cell in our

765
00:48:57,190 --> 00:48:53,180
bodies a friend of mine who is a

766
00:48:59,570 --> 00:48:57,200
biochemist approached one of the large

767
00:49:02,870 --> 00:48:59,580
pharmaceutical companies and said look

768
00:49:05,930 --> 00:49:02,880
you should market something you can call

769
00:49:08,390 --> 00:49:05,940
a super statin you add calculon's I'm

770
00:49:10,970 --> 00:49:08,400
cute into it and you reduce the side

771
00:49:14,180 --> 00:49:10,980
effects and the technical people in the

772
00:49:17,720 --> 00:49:14,190
company were very enthusiastic but it

773
00:49:20,300 --> 00:49:17,730
was vetoed by the legal department who

774
00:49:24,080 --> 00:49:20,310
said that if we start doing this we will

775
00:49:30,420 --> 00:49:24,090
be admitting that we knew that it has

776
00:49:35,200 --> 00:49:33,400
hi Henry my name is Eric shultiess and

777
00:49:39,010 --> 00:49:35,210
I'm from Leiden University Medical

778
00:49:40,570 --> 00:49:39,020
Center there's something going on in the

779
00:49:42,370 --> 00:49:40,580
pharmaceutical industry now there's kind

780
00:49:45,160 --> 00:49:42,380
of a crisis that a lot of the

781
00:49:47,970 --> 00:49:45,170
blockbuster patents are coming to an end

782
00:49:50,380 --> 00:49:47,980
and in the last 20 or 30 years it's been

783
00:49:52,390 --> 00:49:50,390
impossible for the pharmaceutical

784
00:49:54,970 --> 00:49:52,400
industry to replicate the kind of

785
00:49:58,330 --> 00:49:54,980
research that translates into

786
00:50:00,460 --> 00:49:58,340
IP and so I think even within five or

787
00:50:03,280 --> 00:50:00,470
ten years their pharmaceutical industry

788
00:50:04,599 --> 00:50:03,290
is looking at a major downsizing and

789
00:50:07,750 --> 00:50:04,609
it's already beginning to happen I know

790
00:50:08,680 --> 00:50:07,760
with the people that I work with so I'm

791
00:50:10,690 --> 00:50:08,690
just wondering if you could comment

792
00:50:13,240 --> 00:50:10,700
maybe on what's going on in the last 20

793
00:50:17,230 --> 00:50:13,250
years well I think that the drive to

794
00:50:20,190 --> 00:50:17,240
reposition drugs is one indication that

795
00:50:26,250 --> 00:50:20,200
the companies are looking for ways to

796
00:50:29,380 --> 00:50:26,260
keep their their business going I was

797
00:50:34,859 --> 00:50:29,390
interested quite recently to see that

798
00:50:39,430 --> 00:50:34,869
cialis has been repositioned to treat

799
00:50:42,250 --> 00:50:39,440
enlarged prostate for example I think

800
00:50:47,800 --> 00:50:42,260
one of the growth areas that they're

801
00:50:52,140 --> 00:50:47,810
going into is vaccines and one of the

802
00:50:56,800 --> 00:50:52,150
disasters of that already is Gardasil

803
00:51:02,470 --> 00:50:56,810
Gardasil is a vaccine against a few

804
00:51:05,050 --> 00:51:02,480
strains of human papilloma virus which

805
00:51:12,160 --> 00:51:05,060
was found which were found to be

806
00:51:16,380 --> 00:51:12,170
correlated with cervical cancer and the

807
00:51:19,240 --> 00:51:16,390
FDA approved this vaccine which is very

808
00:51:23,589 --> 00:51:19,250
expensive and there have already been

809
00:51:27,870 --> 00:51:23,599
something like 30,000 negative effects

810
00:51:31,359 --> 00:51:27,880
of of Gardasil and you may recall that

811
00:51:34,420 --> 00:51:31,369
people have been enthusiastically

812
00:51:38,440 --> 00:51:34,430
suggesting that every girl be vaccinated

813
00:51:42,650 --> 00:51:38,450
by that Governor Perry did that in in

814
00:51:45,170 --> 00:51:42,660
Texas for a while so I'm afraid the

815
00:51:47,930 --> 00:51:45,180
one of the things that's happening is

816
00:51:52,340 --> 00:51:47,940
that the drug companies are looking to

817
00:51:55,070 --> 00:51:52,350
more and more unwarranted ways of

818
00:51:58,400 --> 00:51:55,080
selling things and they do it because

819
00:52:01,250 --> 00:51:58,410
they're able to advertise to the general

820
00:52:03,080 --> 00:52:01,260
public and what parent of course

821
00:52:06,680 --> 00:52:03,090
wouldn't want to guard their daughter

822
00:52:09,620 --> 00:52:06,690
against cervical cancer this happened by

823
00:52:12,080 --> 00:52:09,630
the way at the same time as for about 20

824
00:52:20,240 --> 00:52:12,090
years the incidence of cervical cancer